Voelcker Academy

Research Symposium 2009


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Reanna Whiterspoon

CCR5 Deletion Impairs the Post-Myocardial Infarction Inflammatory Response

Reanna Whiterspoon

Mentor(s): R. Zamilpa, R. Kanakia, J. Cigarroa, Q. Dai, G. P. Escobar, F. Jimenez, H. G. Martinez, J. Ibarra, S. S. Ahuja and Merry L. Lindsey

The inflammatory response after a myocardial infarction (MI) regulates the wound healing process. Macrophages regulate wound debridement and scar formation. The CC Chemokine Receptor 5 (CCR5) is a key chemokine receptor expressed on macrophages. CCR5 regulates macrophage infiltration. The roles of CCR5 post-MI have not been investigated.